R&D

With 30 years of deep experience in the production field, he has served as a senior executive in production and technology at state-owned enterprises and listed companies, accumulating cross-platform industry insights. Starting his career at the frontline, he is proficient in the technology of API (Active Pharmaceutical Ingredient) factories, equipment operation and maintenance, and the EHS/GMP management system. He also has experience in multiple project constructions, with full-cycle project management capabilities, capable of providing key support for the enterprise's production capacity upgrading and technical optimization.

Master of Organic Chemistry (Nanchang University), Senior Engineer in Organic Chemical Engineering. Won the 1st Prize of Ganzhou Municipal Science and Technology Progress Award (2012) and was named Hangzhou Senior Talent (Category E, 2023). With in-depth experience in API process R&D and synthetic antigen development, he holds 6 authorized patents as the first inventor. Previously at Qingfeng Pharmaceutical Group (as API Workshop Director, Technology Transfer Manager), he led teams to overcome key challenges in Entecavir (market approval, GMP certification) and major projects like Xiyanping Injection. Later at Hangzhou Longji Biotechnology, he led R&D to develop 7 new antigens, combining solid technical reserves and practical problem-solving capabilities.

Graduated from Hunan University's double first-class Chemistry program with a PhD, and has over 10 years of pharmaceutical R&D experience. During his PhD studies, he developed a recyclable, eco-friendly iron-based reduction catalyst (applied in anti-tumor pharmaceutical intermediate synthesis), and completed the R&D, optimization and pilot-scale production of targeted EGFR inhibitor Osimertinib via 6-step synthesis with a 50% overall yield. The related achievements were transferred to Zhejiang-listed pharmaceutical company Aurisco Pharmaceutical for 1.2 million RMB. He also filed 3 patents as first inventor (2 authorized) and published 3 SCI papers. Post-graduation, he served as Pharmaceutical R&D Manager at Wuchan Zhongda Jiangsu Keben Pharmaceutical, and Assistant to the Technical R&D Director at Hunan Daoshi Pharmaceutical Technology. He led the development, optimization and scale-up of lab-scale processes for multiple pharmaceutical and pesticide intermediates, combining solid academic foundation with industrialization capabilities.

Now serving as Peptide R&D Technical Supervisor at Huayao Pharmaceutical, he specializes in the interdisciplinary field of peptides and semiconductors, with proficiency in solid-phase peptide synthesis (SPPS) and semiconductor industrial technology.Previously, he worked at a leading listed peptide drug company as Technical Development Engineer and Researcher, leading lab-scale process development, optimization and scale-up transfer of peptide drug API. He also overcame the application challenges of semiconductor automation in peptide field-completing process verification & optimization for in-situ synthesis of peptide microarray chips, and designing automated production lines.

He has extensive experience in GLP-1 Ras drug semi-synthesis/total synthesis, and in-situ synthesis & automated production of peptide microarray chips. Holding 3 domestic authorized patents and 1 international authorized patent, he provides key technical support for peptide drug R&D and industrialization.

Doctor of Science (graduated from the College of Chemistry and Chemical Engineering, Hunan University) and currently serves as a Professor and Graduate Supervisor at the College of Chemistry and Chemical Engineering, Changsha University of Science and Technology. He has led or participated in 16 national/provincial-level projects, published over 110 high-quality research papers, and led 8 university-enterprise collaborative R&D projects. In the "High-Efficiency Dimethyl Ether Synthesis Technology" project, he developed the first etherification process based on a feedback regulation mechanism-this process increased the product ratio of α- and β-artemether from the traditional ~55/45 to 98/2, breaking the bottleneck of difficult separation and low yield caused by traditional catalysts; he also created a new one-pot semi-synthesis process for vinpocetine (integrating vincamic acid dehydration and esterification in a single pot to realize efficient synthesis), and these two projects alone have created a total economic benefit of RMB 2.5 billion for enterprises. Additionally, he has developed new synthesis processes and technologies for pharmaceutical intermediates such as benflumetol, galantamine, fibrauretin and guanine for relevant enterprises.

Professor, Doctor of Engineering, and Doctoral Supervisor at the College of Chemistry and Chemical Engineering, Hunan University, as well as a Member of the Hunan Provincial Committee of the Chinese Peasants and Workers Democratic Party, Director of its Youth Work Committee, and Deputy Director of the Hunan University Primary Committee. He has published over 90 SCI-indexed research papers and holds more than 50 authorized invention patents (2 transferred to Jinyu New Materials for industrialization, 3 to listed company Aurisco Pharmaceutical). Selected into the Hunan Youth Talents Support Program in 2016, he has won over 10 awards, including the First Prize of Hunan Provincial Natural Science (5th completer, 2024; 2nd completer, 2015), Hunan Provincial Excellent Doctoral Dissertation Award (2014), Hunan Provincial Excellent Petroleum and Chemical Engineer (2016), Hunan Provincial Youth Chemistry and Chemical Engineering Award (2012), and JSPS Fellowship (Japan Society for the Promotion of Science, 2012). He has led over 20 projects (including 5 National Natural Science Foundation of China projects, 4 completed) commissioned by national, provincial/municipal authorities and enterprises, and serves as a reviewer for over 20 international journals, as well as an evaluation expert for National Natural Science Foundation of China and Hong Kong Government Research Grants projects.

Doctor of Science (Hunan University), Postdoctoral Fellow (Peking University), and Master's Supervisor at Central South University of Forestry and Technology. He mainly engages in scientific research in organic synthetic chemistry, pharmaceutical synthesis, synthesis of high-end fine chemicals, and green chemical engineering.

He has led or participated in over ten projects, including those funded by the National Natural Science Foundation of China (NSFC), China Postdoctoral Science Foundation, and Provincial Natural Science Foundation. As first author or corresponding author, he has published over twenty papers in high-level international journals such as Angew. Chem. Int. Ed., Chem. Sci., Org. Lett., and ChemCommun., and holds three authorized national invention patents. He has also led three university-enterprise cooperative projects-among them, the "Green Process Research on Valine-Based Lactam Synthesis" project has created economic benefits of over RMB 10 million for the relevant enterprise.

Graduate background in the College of Chemistry and Chemical Engineering, Hunan University, with a Doctor of Engineering degree; Lecturer and Master's Supervisor at the School of Pharmacy, Gannan Medical University. He mainly engages in scientific research related to medicinal chemistry and synthetic chemistry, having led or participated in 6 national/provincial-level projects and published over 20 SCI-indexed papers.

Graduate background in the College of Chemistry and Chemical Engineering, Hunan University, with a Doctor of Science degree; Lecturer and Master's Supervisor at Hunan Institute of Science and Technology. He has led or participated in 3 national/provincial-level projects, published over 20 high-quality research papers as first/corresponding author, and filed multiple patents.

Doctor of Science, Shanghai Jiao Tong University; Postdoctoral Fellow (College of Chemistry and Chemical Engineering, Hunan University), Assistant Research Fellow, and currently Associate Professor & Graduate Supervisor at Hangzhou Normal University.

He mainly engages in research in asymmetric catalysis, C1 chemistry, and pharmaceutical process design. As first author or corresponding author, he has published over 10 papers in journals including Angew. Chem. Int. Ed., ACS Catal., and Org. Lett., and holds 5 authorized invention patents. He also leads projects such as the National Natural Science Foundation of China (NSFC) Youth Fund, Hunan Provincial Natural Science Foundation Youth Fund, and China Postdoctoral Science Foundation General Program.